In 19- and 20-c. debates that crossed borders among disciplines including psychology, sociology, anthropology, art history, philosophy, and political theory, empathy and alienation emerged as key terms to describe relations among human beings, works of art, and commodities. This seminar addresses the dynamics of empathy and alienation across a range of discourses and artifacts. Our explorations of how empathy and alienation were variously conceptualized in psychological aesthetics, psychoanalysis, and critical theory will aim to open new perspectives on recent debates about identity, affect, and human-animal and human-AI relations.